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Anthracene-9-carboxylic acid
CAS No. 723-62-6
Anthracene-9-carboxylic acid ( —— )
产品货号. M22198 CAS No. 723-62-6
Anthracene-9-carbacid 是一种氯离子转运抑制剂，对 PKA 激活的心脏 IcI 具有中度至强度的抑制作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | ￥235 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Anthracene-9-carboxylic acid
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Anthracene-9-carbacid 是一种氯离子转运抑制剂，对 PKA 激活的心脏 IcI 具有中度至强度的抑制作用。
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产品描述Anthracene-9-carboxylic acid is an inhibitor of chloride transport with a moderate to strong inhibitory action on PKA activated cardiac IcI.
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体外实验Anthracene-9-carboxylic acid causes a voltage-dependent block of outward currents in HEK 293T cells and inhibits a larger fraction of the current as depolarization increased.Anthracene-9-carboxylic acid induces a strong potentiation of tail currents measured at -100 mV after depolarizing voltages, as well as a prolongation of the deactivation kinetics in HEK 293T.Anthracene-9-carboxylic acid (500 μM, rabbit pulmonary artery smooth muscle cells) produces a small inhibition of the maximum outward Cl- current at +70 mV (21±10%) but augmented the amplitude of the instantaneous inward relaxation at -80 mV by 321±34%.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Cl-transport
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研究领域——
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适应症——
化学信息
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CAS Number723-62-6
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分子量222.24
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分子式C15H10O2
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纯度>98% (HPLC)
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溶解度DMSO:22.22 mg/mL (100 mM)
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SMILESOC(=O)c2c1ccccc1cc3ccccc23
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Villegas-Navarro A, Jiménez-Salas Z, Reyes JL. Anthracene-9-carboxylic acid and haematological and biochemical variables in the rat[J]. Archives Internationales De Pharmacodynamie Et De Thérapie, 1989, 302(302):290.
